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Annotated Bibliography: Alzheimer’s and Parkinson’s

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APA format Annotated Bibliography: Alzheimer’s and Parkinson’s
Sabrina Leon
Florida International University
Annotated Bibliography: Alzheimer’s and Parkinson’s
Calderone, A., Formenti, M., Aprea, F., Papa, M., Alberghina, L., Colangelo, A. M., & Bertolazzi, P. (2016). Comparing Alzheimer’s and Parkinson’s diseases networks using graph communities structure. BMC systems biology, 10(1), 1-10.
According to this article, analyzing enormous data sets has recently made it possible to get new insights into current biology and study disease at the systemic level. A new computational technique is described in this article that utilizes the ever-growing “omics” datasets to inform people on Alzheimer’s and Parkinson’s illnesses. Because of the intricate interaction between genetics and the environment, neurological illnesses show an enormous number of molecular abnormalities.

Kluger, B. M., Miyasaki, J., Katz, M., Galifianakis, N., Hall, K., Pantilat, S., … & Kutner, J. S. (2020). Comparison of integrated outpatient palliative care with standard care in patients with Parkinson disease and related disorders: a randomized clinical trial. JAMA neurology, 77(5), 551-560.
Parkinson’s disease and associated illnesses are the 14th most prevalent causes in the United States when it comes to death. Despite the increased interest in palliative care (PC) for individuals with Parkinson’s disease and related disorders (PDRD), there are few research studies that show its efficacy. This disease has existed for a long time and remains one of the most stubborn illnesses among the elderly population.
Mayo, S., Benito-León, J., Peña-Bautista, C., Baquero, M., & Cháfer-Pericás, C. (2021). Recent evidence in epigenomics and proteomics biomarkers for early and minimally invasive diagnosis of Alzheimer’s and Parkinson’s diseases. Current neuropharmacology, 19(8), 1273-1303.

The researchers assert that improperly folded proteins accumulate in the brains of people with Alzheimer’s and Parkinson’s disorders, and it is not too early to think about the processes that control protein expression. The epigenomic and proteomic profiles of these individuals have been examined in several studies, with encouraging findings. These mainly concentrated on early, particular, and noninvasive biomarkers for the diagnosis and prognosis of Alzheimer’s and Parkinson’s disease.
Bencs, V., Bencze, J., Módis, V. L., Simon, V., Kálmán, J., & Hortobágyi, T. (2020). Pathological and clinical comparison of Parkinson’s disease dementia and dementia with Lewy bodies. Orvosi hetilap, 161(18), 727-737.
The authors argue that Dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) share clinical, pathophysiological, and morphologic characteristics, making them important neurodegenerative disorders. LBs are more often seen in the cortex of people with DLB than they are in those with PDD. As a result, in DLB, concurrent Alzheimer’s disease (AD), pathology with -amyloid plaques and neurofibrillary tangles are more prevalent, and it is still contested whether DLB and PDD are two independent species or separate phenotypes of the same illness.
Gurnani, A. S., & Gavett, B. E. (2017). The differential effects of Alzheimer’s disease and Lewy body pathology on cognitive performance: a meta-analysis. Neuropsychology review, 27(1), 1-17.
Gurnani and Gavett (2017) assert that differentiating Alzheimer’s disease (AD) from other types of dementia and the natural aging process is critical for the development of effective treatment choices and long-term care solutions. AD. When it comes to the diagnosis of neurodegenerative illness, pathological evidence is the gold standard, yet existing studies on the use of neuropsychological tests in the alternative diagnosis of dementia depend on clinical diagnostic results. According to the research presented in this study, there are cognitive assessments and areas that enable for the distinction of AD patients from those with dementia with Lewy bodies (DLB) or other forms of dementia.
Cubo, E., Doumbe, J., Martinez-Martin, P., Rodriguez-Blazquez, C., Kuate, C., Mariscal, N., … & ELEP Group. (2014). Comparison of the clinical profile of Parkinson’s disease between Spanish and Cameroonian Cohorts. Journal of the neurological sciences, 336(1-2), 122-126.
According to this article, as the aged population in wealthy nations increases, so does the prevalence of Parkinson’s disease (PD), a neurodegenerative brain illness. Some have hypothesized that Parkinson’s disease (PD) prevalence among sub-Saharan African communities is lower than that of other groups because of discrepancies in case finding techniques and diagnostic criteria, and early death. On the other hand, rapid demographic shifts suggest that the frequency of PD may be rising in Sub-Saharan nations. Dorszewska, J., & Kozubski, W. (Eds.). (2018). Alzheimer’s Disease: The 21st Century Challenge. BoD–Books on Demand.
According to this book, the progress in technology and medicine in the second half of the 20th century has increased life expectancy. This is coupled with a greater incidence of illnesses that are primarily meant for old age, such as Alzheimer’s disease. It is believed that the incidence of this disease is primarily pegged on old age, and it is currently regarded as incurable with unclear etiology.
References
Bencs, V., Bencze, J., Módis, V. L., Simon, V., Kálmán, J., & Hortobágyi, T. (2020). Pathological and clinical comparison of Parkinson’s disease dementia and dementia with Lewy bodies. Orvosi hetilap, 161(18), 727-737.
Calderone, A., Formenti, M., Aprea, F., Papa, M., Alberghina, L., Colangelo, A. M., & Bertolazzi, P. (2016). Comparing Alzheimer’s and Parkinson’s diseases networks using graph communities structure. BMC systems biology, 10(1), 1-10.
Cubo, E., Doumbe, J., Martinez-Martin, P., Rodriguez-Blazquez, C., Kuate, C., Mariscal, N., … & ELEP Group. (2014). Comparison of the clinical profile of Parkinson’s disease between Spanish and Cameroonian Cohorts. Journal of the neurological sciences, 336(1-2), 122-126.
Dorszewska, J., & Kozubski, W. (Eds.). (2018). Alzheimer’s Disease: The 21st Century Challenge. BoD–Books on Demand.
Gurnani, A. S., & Gavett, B. E. (2017). The differential effects of Alzheimer’s disease and Lewy body pathology on cognitive performance: a meta-analysis. Neuropsychology review, 27(1), 1-17.
Kluger, B. M., Miyasaki, J., Katz, M., Galifianakis, N., Hall, K., Pantilat, S., … & Kutner, J. S. (2020). Comparison of integrated outpatient palliative care with standard care in patients with Parkinson disease and related disorders: a randomized clinical trial. JAMA neurology, 77(5), 551-560.
Mayo, S., Benito-León, J., Peña-Bautista, C., Baquero, M., & Cháfer-Pericás, C. (2021). Recent evidence in epigenomics and proteomics biomarkers for early and minimally invasive diagnosis of Alzheimer’s and Parkinson’s diseases. Current neuropharmacology, 19(8), 1273-1303.

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