https://professorspeedy.com/wp-admin/options-general.php?page=header-footer/admin/options.php

Muscular Histology Case Study

Place your order now for a similar assignment and have exceptional work written by our team of experts, At affordable rates

For This or a Similar Paper Click To Order Now

Take Test: Muscular Histology Case Study
Chief ComComplaint: 19-year-old non-ambulatory male with pneumonia.
History: James Fenlow, a 19-year-old male, is immobile and hospitalized for pneumonia. He has a long history of progressive weakening of his muscles. In the first year of his life, James reached many gross motor skill milestones, such as holding his head up, rolling over, sitting, and standing, at normal times. However, he did not walk until age 16 months, and by age two, started to assume a lordotic posture while standing but not while sitting. A Gower’s sign was noted by age four, as was a Trendelenberg gait. Over the next several years, he suffered progressive muscle weakness, most notably in the proximal musculature of the arms, pelvis, and legs. By age 9, he required orthotic braces to assist his walking, and by age 11, he was confined to wheelchair ambulation. In his early teen years, James was still able to use eating utensils, write, and type on a keyboard, though these functions have declined over the past year. At 16, he was hospitalized with bronchitis requiring antibiotic treatment, but recovered. Throughout the years, James has had no history of muscle pain or spasm, chest pain, or irregular heartbeat. He was diagnosed with a learning disability in the fourth grade, but has progressed through the grades with tutorial assistance. The only medications that he normally takes are calcium and fluoride supplements. James has a younger sister in good health and a younger brother (age 10) who is confined to a wheelchair with problems similar to James’s. No other immediate or distant family members have musculoskeletal difficulties.
Physical Examination: On examination, James appeared fatigued and short of breath. Vital signs: (1) heart rate = 104 beats per minute, (2) respiratory rate = 28 breaths per minute, (3) temperature (oral) = 102.4 degrees F, and (4) blood pressure = 138 / 74. Pupils were normal and reactive to light, with ocular movements intact. No dysarthria or facial muscle weakness was noted. Percussion of the thorax suggested pulmonary infiltrates in the lower lung fields bilaterally. Breath sounds were reduced, with significant inspiratory rales heard over both lungs. His cough was very weak, but productive of green sputum. Heart sounds were normal, with no murmur. Bowel sounds were normal. Musculoskeletal exam revealed a scoliotic deformity of the spine when James sat up. Upper chest, shoulder, and thigh muscles were significantly atrophied, but the calf muscles appeared enlarged. Bilateral elbow contractures limited elbow extension to 80 degrees. Bilateral Achilles contractures were also present. Muscle strength was reduced in the biceps and triceps brachii muscles bilaterally (+2 on a scale from 0 to +5, +5 being normal), deltoids (+1), and he was not able to move either thigh into flexion or extension. Muscle stretch reflexes (rated on a scale from 0 to +4, +2 being normal) were as follows: right and left biceps and triceps brachii (+1), right and left brachioradialis (+1), right and left patellar reflexes (0), and right and left ankle jerks (+1). I
Complete the case study using information from your text book and web resources.
QUESTION 1
1. At age 4, James underwent a biopsy of the right gastrocnemius muscle.
The pathologist’s report noted histopathologic changes suggestive of Duchenne muscular dystrophy.
Describe in detail the typical microscopic and cellular changes noted in the muscle tissue of someone with Duchenne’s muscular dystrophy.
QUESTION 2
1. Which muscles are most severely affected by this disease as the disease progresses? The muscle mostly affected by the disease
What is the usual progression over time?
QUESTION 3
1. What is dystrophin and how does it related to James’ disease? How is distribution of dystrophin determined in the histology laboratory? What are the major microscopic differences between healthy muscle tissue and DMD muscle tissue?

For This or a Similar Paper Click To Order Now

What Will You Get?

We provide professional writing services to help you score straight A’s by submitting custom written assignments that mirror your guidelines.

Premium Quality

Get result-oriented writing and never worry about grades anymore. We follow the highest quality standards to make sure that you get perfect assignments.

Experienced Writers

Our writers have experience in dealing with papers of every educational level. You can surely rely on the expertise of our qualified professionals.

On-Time Delivery

Your deadline is our threshold for success and we take it very seriously. We make sure you receive your papers before your predefined time.

24/7 Customer Support

Someone from our customer support team is always here to respond to your questions. So, hit us up if you have got any ambiguity or concern.

Complete Confidentiality

Sit back and relax while we help you out with writing your papers. We have an ultimate policy for keeping your personal and order-related details a secret.

Authentic Sources

We assure you that your document will be thoroughly checked for plagiarism and grammatical errors as we use highly authentic and licit sources.

Moneyback Guarantee

Still reluctant about placing an order? Our 100% Moneyback Guarantee backs you up on rare occasions where you aren’t satisfied with the writing.

Order Tracking

You don’t have to wait for an update for hours; you can track the progress of your order any time you want. We share the status after each step.

image

Areas of Expertise

Although you can leverage our expertise for any writing task, we have a knack for creating flawless papers for the following document types.

Areas of Expertise

Although you can leverage our expertise for any writing task, we have a knack for creating flawless papers for the following document types.

image

Trusted Partner of 9650+ Students for Writing

From brainstorming your paper's outline to perfecting its grammar, we perform every step carefully to make your paper worthy of A grade.

Preferred Writer

Hire your preferred writer anytime. Simply specify if you want your preferred expert to write your paper and we’ll make that happen.

Grammar Check Report

Get an elaborate and authentic grammar check report with your work to have the grammar goodness sealed in your document.

One Page Summary

You can purchase this feature if you want our writers to sum up your paper in the form of a concise and well-articulated summary.

Plagiarism Report

You don’t have to worry about plagiarism anymore. Get a plagiarism report to certify the uniqueness of your work.

Free Features $66FREE

  • Most Qualified Writer $10FREE
  • Plagiarism Scan Report $10FREE
  • Unlimited Revisions $08FREE
  • Paper Formatting $05FREE
  • Cover Page $05FREE
  • Referencing & Bibliography $10FREE
  • Dedicated User Area $08FREE
  • 24/7 Order Tracking $05FREE
  • Periodic Email Alerts $05FREE
image

Our Services

Join us for the best experience while seeking writing assistance in your college life. A good grade is all you need to boost up your academic excellence and we are all about it.

  • On-time Delivery
  • 24/7 Order Tracking
  • Access to Authentic Sources
Academic Writing

We create perfect papers according to the guidelines.

Professional Editing

We seamlessly edit out errors from your papers.

Thorough Proofreading

We thoroughly read your final draft to identify errors.

image

Delegate Your Challenging Writing Tasks to Experienced Professionals

Work with ultimate peace of mind because we ensure that your academic work is our responsibility and your grades are a top concern for us!

Check Out Our Sample Work

Dedication. Quality. Commitment. Punctuality

[display_samples]

It May Not Be Much, but It’s Honest Work!

Here is what we have achieved so far. These numbers are evidence that we go the extra mile to make your college journey successful.

0+

Happy Clients

0+

Words Written This Week

0+

Ongoing Orders

0%

Customer Satisfaction Rate
image

Process as Fine as Brewed Coffee

We have the most intuitive and minimalistic process so that you can easily place an order. Just follow a few steps to unlock success.

See How We Helped 9000+ Students Achieve Success

image

We Analyze Your Problem and Offer Customized Writing

We understand your guidelines first before delivering any writing service. You can discuss your writing needs and we will have them evaluated by our dedicated team.

  • Clear elicitation of your requirements.
  • Customized writing as per your needs.

We Mirror Your Guidelines to Deliver Quality Services

We write your papers in a standardized way. We complete your work in such a way that it turns out to be a perfect description of your guidelines.

  • Proactive analysis of your writing.
  • Active communication to understand requirements.
image
image

We Handle Your Writing Tasks to Ensure Excellent Grades

We promise you excellent grades and academic excellence that you always longed for. Our writers stay in touch with you via email.

  • Thorough research and analysis for every order.
  • Deliverance of reliable writing service to improve your grades.
Place an Order Start Chat Now
image